Modulation of asymmetric cell division as a mechanism to boost CD8+ T cell memory
M Borsa, I Barnstorf, NS Baumann, K Pallmer… - Science …, 2019 - science.org
… Using the murine LCMV infection model, we established a … linked to cell stemness, as only
naïve and memory CD8 + T cells could … memory T cell generation in adoptive transfer settings. …
naïve and memory CD8 + T cells could … memory T cell generation in adoptive transfer settings. …
CD8+ T cell metabolism in infection and cancer
M Reina-Campos, NE Scharping… - Nature Reviews …, 2021 - nature.com
… killing of infected cells, while long-lived memory CD8 + T cell … using this in vitro system
suggested that memory CD8 + T … to couple oxidative phosphorylation with the generation of ATP …
suggested that memory CD8 + T … to couple oxidative phosphorylation with the generation of ATP …
[HTML][HTML] CD4+ T cell help creates memory CD8+ T cells with innate and help-independent recall capacities
T Ahrends, J Busselaar, TM Severson, N Bąbała… - Nature …, 2019 - nature.com
… T cell help on the generation of memory CD8 + T cell subsets in a model of overt inflammation.
Mice were infected with the acute … the replicates for each cell type using samtools and …
Mice were infected with the acute … the replicates for each cell type using samtools and …
[HTML][HTML] Signature of long-lived memory CD8+ T cells in acute SARS-CoV-2 infection
… Here, using spectral flow cytometry combined with cellular … -Dex + cells longitudinally,
at both the population level and … for memory generation 34 . As we sampled SARS-CoV-2-specific …
at both the population level and … for memory generation 34 . As we sampled SARS-CoV-2-specific …
[HTML][HTML] Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
… of IFNγ + T cells ± SEM; Percentage shown on top of the … may have led to the generation
of T cell immunity even in the … contacts and 30 healthy donors by using an overnight “ex vivo” …
of T cell immunity even in the … contacts and 30 healthy donors by using an overnight “ex vivo” …
CD4+ T help promotes influenza virus-specific CD8+ T cell memory by limiting metabolic dysfunction
JG Cullen, HA McQuilten, KM Quinn… - Proceedings of the …, 2019 - National Acad Sciences
… to establishing optimal CD8 + T cell memory generation and … priming ensures that memory
CD8 + T cells are programmed … assessed oxygen consumption rates (OCR) using a Seahorse …
CD8 + T cells are programmed … assessed oxygen consumption rates (OCR) using a Seahorse …
Cytokine-mediated regulation of CD8 T-cell responses during acute and chronic viral infection
… using IL-2-deficient mice showed that antiviral CD8 T-cell … CD8 T cells did not show any
impairment for the generation … Memory CD8 T cells induced after a primary acute infection …
impairment for the generation … Memory CD8 T cells induced after a primary acute infection …
The architectural design of CD8+ T cell responses in acute and chronic infection: Parallel structures with divergent fates
… goal of generating large numbers of effector T cells to help … Comparative analyses of the
effector and memory CD8 + T cell … As the determination of cell subsets or states using single-cell …
effector and memory CD8 + T cell … As the determination of cell subsets or states using single-cell …
SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses
…, T Amarasena, G Taiaroa, P Kinsella, KC Liew, T Tran… - Immunity, 2023 - cell.com
… Using 6 pMHC multimers in a cohort with early and frequent … of recalled and primary T cell
responses following Delta or … whether T cell recall kinetics correlate with the levels and rate of …
responses following Delta or … whether T cell recall kinetics correlate with the levels and rate of …
[HTML][HTML] Stochastic episodes of latent cytomegalovirus transcription drive CD8 T-cell “memory inflation” and avoid immune evasion
M Griessl, A Renzaho, K Freitag, CK Seckert… - Frontiers in …, 2021 - frontiersin.org
… the memory CD8 + T-cell response to natural infections with … of MI by generating the
epitope-specific cells that can later be re-… of peptide-specific CD8 + T cells was performed using …
epitope-specific cells that can later be re-… of peptide-specific CD8 + T cells was performed using …